Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases Research Published on 2022-03-192022-10-05 Journal: Scientific Reports [Category] 치료제, [키워드] Aede Anophele Chloroquine condition DENV-2 derivative disease Effect effective Efficacy exhibited growth Host IC50 insecticidal lack malaria malarial mice Mosquito P. falciparum Plasmodium falciparum populations purified serotype Spread strain synthesis Toxicity vector vectors viral pathogen virucidal [DOI] 10.1038/s41598-022-08397-5 [Article Type] Research
Successful Reversal of the 2020 Covid-19 Response Induced Collateral Damage on Malaria Control in Saudi ArabiaConference abstract Published on 2022-03-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 유전자 메커니즘, [키워드] activities analyzed Anophele Can Collateral Control correlated Coverage COVID-19 COVID-19 pandemic damage Environment Epidemic indicated induced lockdown malaria malaria control management material one health outbreak pandemic Patient patients treated platform positive post intervention post-intervention precipitated Program protocol provided recorded reduction reductions in reflected residual response Result reversal Saudi Arabia Support Surveillance Transmission treated water WHO [DOI] 10.1016/j.ijid.2021.12.288 [Article Type] Conference abstract
Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii전체 게놈 시퀀싱 및 전 사체의 통합은 주요 말라리아 벡터 Anopheles coluzzii에서 살충제 저항성의 재건에 대한 복잡한 그림을 보여줍니다.Research Article Published on 2021-12-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] alteration Anophele approach block change changes in colony complex complexity determine diagnostic Diagnostic markers elevated expression of gene Genetic genetic background Genome genomic genomic change increase in increased respiratory rate increasingly insecticide integration inversion Laboratory malaria malaria control malaria vector marker mechanism metabolism microbial Microbiome original oxidative phosphorylation pathway phenotype Population Pyrethroids respiratory rate reveal RNAseq Sequencing subject subset susceptible Transcriptome transcriptomic transcriptomics translated whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1009970 PMC 바로가기 [Article Type] Research Article
Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus서아프리카 Anopheles의 pirimiphos-methyl에 대한 내성은 Ace1 유전자좌의 복제 및 유전자이입을 통해 확산되고 있습니다.Research Article Published on 2021-01-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] ACE1 acetylcholinesterase African Analysis analysis Anophele Anopheles gambiae approach association Carbamate Combination complex Control copy number diagnostic dominant driven by duplication duplications effective Effectiveness enzyme Genetic genomes genomic Haplotype highlight increasingly insecticidal insecticide insecticides Intervention locus malaria malaria vector molecular Mutation Non-synonymous occur organophosphate overcome phenotypic pirimiphos-methyl Population populations Predictive Predictive value predictor Prevent provide public health reduce Replication resistance resistance mechanism resistance mechanisms selection pressure sequenced specimen Spread sub-Saharan Africa Surveillance transferred Transmission unique Variation vector vectors West whole genome [DOI] 10.1371/journal.pgen.1009253 PMC 바로가기 [Article Type] Research Article
An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons말라리아 매개체 Anopheles funestus의 살충제 저항성의 아프리카 전역 게놈 진화에는 선택적 스윕, 복제 수 변이, 유전자 전환 및 트랜스포존이 포함됩니다Research Article Published on 2020-06-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] alleles Analysis analysis Anophele approach bed net complex copy number cytochrome P450 driven by Effectiveness Evidence evidence of Evolution exhibited gene conversion gene flow Genes genetic diversity genomic genomic change genomic region glutathione greater haplotypes highlighting independent insecticide insecticides insertion Intervention Local loci locus malaria malaria control malaria vector management metabolic Metabolic resistance molecular molecular evolution Multiple performed Population pyrethroid respond risk selection pressure selective sweep selective sweeps signature Spread Temporal transposon Variation variations vector control whole genome [DOI] 10.1371/journal.pgen.1008822 PMC 바로가기 [Article Type] Research Article
Experimental population modification of the malaria vector mosquito, Anopheles stephensi말라리아 매개 모기인 Anopheles stephensi의 실험적 개체군 변형Research Article Published on 2019-12-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 1:1 accumulation Anophele anticipated approach Asian Author can be used Cas9 caused cleavage Effect Efficacy Efficiency effort evaluated exhibited exhibiting expected experimental design extinction favor feature female Genetic genetics Genome genomic IMPROVE in some insect Insects Kynurenine Laboratory malaria malaria vector male methodology Modification much lower Mutagenesis NHEJ nonhomologous open overlapping percentages Population populations prevented problem reached recent Release released repeated reproductive resulting Spread strain Strains survival target gene Target genes transgene Transmission Trial vector-borne diseases were used while [DOI] 10.1371/journal.pgen.1008440 PMC 바로가기 [Article Type] Research Article